Molnár-Institute announces new DryLab® Masterclasses for 2019

Molnár-Institute announces new DryLab® Masterclasses for 2019

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Press Release | Molnár-Institute for applied chromatography

DECEMBER 06, 2018

The Molnár-Institute for Applied Chromatography will host a new series of Masterclasses on HPLC & UHPLC method development, as well as Separation of Therapeutic Proteins (Biopolymers), using its proprietary DryLab®4 separation modelling software.

The three day DryLab® (U)HPLC Method Development Masterclasses will follow the format of the successful 2018 series and will again be held at the Molnár-Institute in Berlin during spring and autumn 2019, with exact dates to be announced.

The classes will provide ‘hands on’ interactive training in DryLab®4 modeling and processes, helping users to improve and transfer methods, focusing on decreasing run times while maintaining selectivity.

The courses also teach participants systematically to develop by creating multidimensional DryLab®4 models depicting the interaction of up to 12 influential HPLC parameters, for superior regulatory compliance and faster market entry.

DryLab® Masterclass Modules

Each Masterclass comprises a series of modules, including:

  • Optimization of Gradient Profiles and Critical Resolution in (U)HPLC: Design and Optimization of Gradient Profiles. Forecast and Control of Peak Movements. Evaluation of Gradient Effects on Resolution. Strategies for Separation of Small and Large Molecules.
  • Efficient (U) HPLC Method Development: Design Space Visualization. Extensive Reduction of Method Development Time Across HPLC Types (RP, NP, HIC, HILIC, IEX). Significant Method Runtime Reduction. Evaluation of Method Robustness and Determination of MODR.
  • Regulatory Compliance and Data Integrity: Compliance with FDA and EMA Regulations. Demands on Inspection Proof Methods. QbD Principles for Analytical Method Development. Recording of Full Method Development Cycle. Knowledge Management Documentation for Data Safety and Integrity.
  • Method Transfer Management: Requirements for Transfer Safe Methods. Post Transfer Management and OoS Handling. Control of Instrument Specifications and Their Influence on Selectivity. Substitution of Outdated Columns.
  • Method Design and Redesign: Advanced Method Design for Bioseparations. Conversion of Obsolete and Outdated Methods. Multi-Column Method Design. Method Transfer to Modern (U)HPLC Instrumentation.
  • Efficient Eluent and Solvent Management: In-Silico Analysis. Development of Economic and Ecologically Favorable Methods. Extension of Column Lifetime. Optimized Utilization of Solvents. Finding of Alternative Eluents.

Early registration discount

Molnár-Institute courses are taught in English by Dr. Hans-Jürgen Rieger, Vice President for Product Marketing, along with the Institute’s scientists Arnold Zöldhegyi and Halina Katsialevich. Each brings in-depth knowledge and experience to the classroom in both theory and practice of HPLC.

Registrations made 10 weeks prior to start of course will qualify for 25 per cent discount on seminar fee.

Molnár-Institute can also offer similar in-house courses in English or German at company locations worldwide.

About Molnar-Institute

Molnár-Institute for applied chromatography focuses on new strategies for improving the efficiency and success of modern high-performance liquid chromatography (HPLC) through its method development software DryLab®4, HPLC and software training courses, and HPLC consulting.

Since its foundation in 1981, by Dr. Imre Molnár in Berlin, Molnár-Institute has followed a consistent mission, to form a center of excellence to save, reduce and optimize method development and run time in HPLC.

The institute supports ongoing research and development at universities and corporations worldwide with a team of chromatography specialists devoted to improving global health care and to ensuring the development of safe and effective products in the pharmaceutical, life-science, and food industries.

By applying its proprietary method development software DryLab®4 in conjunction with rigorous methodologies, the institute is able to optimize method development and reduce method run time in HPLC and UHPLC. Using real data from a minimal number of experimental runs, DryLab® builds multi-dimensional selectivity maps depicting the interaction of the most important parameters influencing an HPLC separation. This systematic, guided method development process can halve development time, help users optimize parameters based on their specific method goals, and enable easier compliance with regulatory standards (QbD).

Dr. Imre Molnár remains president of the Molnar-Institute, which is a privately-owned organisation, headquartered in central Berlin.

Media Contact

Magdalena Marinski, Marketing and Account Manager, Molnár-Institute for applied chromatography
Tel.: +49 30 421 5590


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Supplier Information
Supplier: Molnár-Institute for applied chromatography
Address: Schneegloeckchenstrasse 47, 10407 Berlin, Germany
Tel: +49 30 421 559-0
Fax: +49 30 421 559-99

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