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    MEDELPHARM demonstrates compaction simulation capabilities at UK Tabletting School

    July 2nd 2024

    Beynost, (Lyon), France: – Research-based manufacturer and powder compaction specialist MEDELPHARM has demonstrated its extensive compaction simulation capabilities at the 2024 edition of the Tabletting School hosted by BASF Pharma and De Montfort University (DMU) at Leicester, in the UK.

    The school consisted of varied workshop sessions held over two days between June 18th and 19th, 2024, that included MEDELPHARM’s benchtop-sized STYL’One Nano R&D compaction simulator.

    Hands-on demos

    The workshops also featured hand-on sessions with an XL 100 R&D Rotary Tablet Press from parent company KORSCH AG, to show how data collected on the STYL’One Nano can be fed through to pilot production.

    MEDELPHARM has been a regular participant and contributor to the DMU Tabletting School since its inception in 2019.  As specialists in powder compaction technology, its team of formulation scientists has also been able to provide students and researchers with valuable insights into formulation, galenic research, tableting and scale-up.

    Formulation and scale-up

    This year’s agenda included a Workshop on ‘Evaluation of a powder blend using a compaction simulator’ facilitated by MEDELPHARM Science Lab Global Coordinator Bruno Leclercq, with assistance from Formulation Scientist Dr. Lucile Kubiak. The session showed a data-driven methodology for material characterization and formulation development in a material-sparing approach, using the STYL’One Nano.

    Mr. Leclercq was joined by Process Specialist Dr. Friederike Gütter of the KORSCH Innovation Center to co-host a further session ‘Bilayer tablet formulation, from R&D to production’ that demonstrated definition of optimal process parameters on STYL’One Evo to reach tablet quality attributes for a bilayer formulation before production on a KORSCH X 3 Tablet Press.

    Dr. Gütter also delivered a lecture on ‘Scaling-up of tabletting processes’, that highlighted the key role of  compaction simulation in not only enabling drug product development with minimum quantities of API, but also providing a firm base for up-scaling procedures for high-speed production on rotary presses.

    Compaction simulators like the STYL’One Nano are integral to the Quality by Design (QbD) approach, providing valuable insights during the tablet development stage. This proactive use allows for the determination of optimal process parameters, the selection of appropriate tooling, and the identification of the ideal API-excipient combination with minimal material use. By enabling data-driven decision-making early in the process, R&D tablet presses help prevent issues and defects that could arise during production.

    Sharing insights and ideas

    In addition, Dr. Gütter facilitated a workshop on ‘Formulation assessment and process optimization on R&D rotary press XL 100’ in which she showed how formulation properties could be aligned with chosen tablet press in development to enable optimal manufacturing.

    Bruno Leclercq commented: “We are always delighted at MEDLPHARM to participate in the DMU Tabletting School that provides valuable opportunities to share knowledge and insights directly with participants, get their feedback, discuss ideas, and identify future challenges.”


    Headquartered near Lyon, MEDELPHARM is a high-precision engineering company manufacturing R&D tablet presses and providing innovative solutions for powder analysis and formulation.

    Since 1985, MEDELPHARM has been the specialist in tableting instruments ‘Made by people for people’, with high-speed and precision but at the same time very easy-to-use.

    Since the end of 2022, it has been a member of the international KORSCH Group, enhancing its worldwide reach.

    For more information, visit:


    Click on MEDELPHARM Instruments to learn more.
    Click on BASF Pharma/DMU Tabletting School 2024 for further information.


    Troubleshooting Tablet Defects in No-Time

    MEDELPHARM demonstrates compaction simulation capabilities at UK Tabletting School

    MEDELPHARM Science Lab team providing insights into the evaluation of a power blend using the STYL’One Nano.

    MEDELPHARM demonstrates compaction simulation capabilities at UK Tabletting School

    Dr. Friedericke Gütter from KORSCH AG demonstrating KORSCH XL 100 R&D rotary tablet press.

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