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    Headquartered near Lyon, Medelpharm is a high-precision engineering company manufacturing R&D tablet presses and providing innovative solutions for powder analysis and formulation.

    Since 1985, Medelpharm have been specialists in designing and manufacturing tableting instruments that work with high-speed and precision but at the same time are easy-to-use, summarized in the strapline: ‘Made by people for people’.

    With its background in actual production, Medelpharm has a deep understanding of tableting processes.

    For formulation scientists and pilot plant developers around the world looking for assistance in powder characterization, solid dosage formulation or production trouble shooting, Medelpharm can offer a comprehensive portfolio of multi-functional tableting Instruments, R&D presses and high-speed compaction simulators as well as process equipment and extensive Science lab services in tableting, early research API characterization all the way to product development.

    Products and Services

    Research Presses for API characterization and raw materials and tablet formulations

    Medelpharm focuses on continuous development of innovative research presses (hardware and software), simulation of industrial production cycles, powder characterization and formulation services, compression- and material science in the pharmaceutical, food and cosmetics market.

    The latest revolutionary Benchtop R&D tablet press, the STYL’One Nano is the latest example of Medelpharm’s expertise and creativity. Tableting research has never been so easy and so powerful, from pure API characterization to formulation assessment. Fully instrumented with standard B&D tooling, this tableting instrument is controlled by software in force or position mode. Pre- and main compression provides benefits found on small rotary presses while square and saw tooth profile allow you to further characterize your formula. Building your own API & excipient database is an easy task with Nano.

    The STYL’One Evolution tableting instrument, now in its fourth generation, is a high-speed all-in-one multilayer tool from early formulation to scale-up at production speed. The machine characterizes essential powder properties and active pharmaceutical ingredients (API) and tests their suitability by simulating industrial production cycles with only a few grams of powder needed. The STYL’One Evolution is designed for ease of use, compact footprint, and offers a clean and easy exchange of B, D (EU │TSM) oversized, core rods. Optional micro-dosing unit; tab-in-tab device and GMP module with weight regulation and force feeding as well as a heated die are just a few of the available accessories offered with production mind.

    Medelpharm STYLCAM and STYL’One units have been installed by more than 150+ customers worldwide.

    No compromise operator protection

    From early research to multilayer production scale-up, Medelpharm recognizes global trends for more stringent regulation and increased emphasis on operational exposure limits and environmental protection. Accordingly, it stresses the whole range of operator protection from wash-in-place (WIP) to full containment, for the most potent drugs substances.

    Small scale development in dry granulation

    Dry granulation with roll compaction hybrid modelling is a topic intensively pursued by Medelpharm in intensive cooperation with University of Düsseldorf.

    QbD in tablet formulation

    Quality by Design (QbD), a concept to produce a drug in a repeatable manner and cost-effective way, is in the heart of the design of the STYL’One R&D press.

    High-power, adaptable software for powder compaction analysis

    The data acquisition and control packages automatically explores and analyses the design of formula with efficiency in investigating critical attributes. Collected data is analyzed and presented in a user-friendly tabular or graphical format.

    Science Tableting Laboratory services –resource for optimal tableting

    Understanding your APIs and excipients is essential to design robust formulations and production processes. Our science lab is here to help to generate data and interpret results from simple compatibility profiles to in-depth porosity, radial stress and elastic recovery analysis. We can guide you in your R&D, even with only a few grams of powder.

    It houses a full range of leading-edge measuring equipment along with STYL’One EVO and STYL’One Nano Benchtop Tableting Instruments, Smart test 50 and Mini coater/drier for coating of minimal quantities of tablets as well as an SLS multifunctional mill and sifter.

    A team of junior and senior scientists is assigned to each powder characterization project to screen numerous formulations and test powder flowability, powder densities and tablet formulations.

    Training to maximize R&D and production capabilities

    Investment in training today means time-saving tomorrow. Medelpharm is a training center recognized by the French authorities.

    High level research

    The students should get the opportunity to use professional tableting instruments for their training and getting experience on future working methods and machines. Medelpharm has chosen to put co-operation with universities at the heart of its strategy with partnerships all over the world.

    Specialist services

    Medelpharm offers a range of targeted specialist services for commissioning and validation, application training, maintenance and calibration.

    Powder processing solutions

    Medelpharm distributes renowned and innovative technologies in powder processing from Lab scale to production, in association with partners worldwide, including:

    • LB Bohle: Leading supplier of special process machines for the pharmaceutical industry Manufacturer of equipment for weighing, granulation, sieving, blending and coating.
    • Caleva: Market leader in manufacturing and developing equipment for the production of pellets (beads or spheroids) by extrusion and spheronization™
    • Fitzpatrick: Leading manufacturer of pharmaceutical hammer mills
    • Quadro: Renowned manufacturer inventor of conical mills for consistent size reduction and uniform tableting, with world-leading technologies for achieving uniform size reduction, sieving, de-agglomeration and dispersion.
    • ProCepT: Specialist in lab-scale R&D equipment, offering innovative solutions for drying, agglomeration, tablet coating and mixing applications. Focusing on small-scale equipment.

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