MEDELPHARM

Headquartered near Lyon, MEDELPHARM is a high-precision engineering company manufacturing R&D tablet presses and providing innovative solutions for powder characterization and formulation.

Since 1985, MEDELPHARM is a specialist in tableting instruments “Made by people for people”, that work with high-speed and precision but at the same time are very easy-to-use.

With its historical background in actual production, MEDELPHARM has a deep understanding of the R&D requirements that apply to tableting processes.

For formulation and pilot plant scientists around the world looking for assistance in powder characterization, solid dosage formulation or production troubleshooting, MEDELPHARM can offer a comprehensive portfolio of versatile R&D presses and high-speed compaction simulators supported by a team of dedicated scientists.

Since the end of 2022, it has been a member of the international KORSCH Group, enhancing its worldwide reach.

Products and Services

For scientists around the world looking for assistance in powder characterization, solid dosage formulation or production troubleshooting, MEDELPHARM can offer a comprehensive portfolio of versatile R&D tablet presses and high-speed compaction simulators supported by a team of dedicated scientists. As compressed powders can be found everywhere, the applications encompass the pharmaceutical, cosmetics, food and nutraceuticals, chemistry & detergents, batteries & catalysts and explosives & nuclear industries.

MEDELPHARM Instruments

MEDELPHARM’s range of tableting instruments support a QbD approach of oral solid dose manufacturing, and cover every step of the process, from powder characterization, to formulation development, and scale-up.

The STYL’One Nano is the revolutionary benchtop R&D tablet press for demanding formulation scientists with price performance in mind. From API/excipient characterization, analytical development to formulation feasibility assessment and optimization, develop your single-layer formulation with only a few grams of powder.

The STYL’One Evo versatile compaction simulator, now in its fourth generation, is a high-speed all-in-one single and multilayer tool from early formulation to scale-up at production speed. The machine characterizes essential powder properties and active pharmaceutical ingredients (API) and tests their suitability by simulating industrial production cycles with only a few grams of powder needed. The STYL’One Evo is designed for ease-of-use, compact footprint, and offers easy exchange of B, D (EU │TSM), oversized or core rods tooling. An optional micro-dosing unit, tab-in-tab device, GMP module with weight regulation, and force feeding are just a few of the available accessories offered with production mind.

MEDELPHARM’s STYL’One DryCon® and WipCon® offer various solutions for the pharmaceutical industry’s requirements regarding containment and isolation.

More than 250 MEDELPHARM STYL’One units have been installed worldwide.

MEDELPHARM Science Lab

MEDELPHARM’s tableting and powder characterization laboratory houses a team of research scientists and a range of sophisticated instrumentation dedicated to supporting clients with their product development needs. These include material characterization, scale-up, small batch production, formulation, troubleshooting and tableting training courses.

Since in-depth understanding of API and excipient properties is essential to design robust formulations and production processes, the MEDELPHARM Science Lab was created to generate data and interpret results from simple compatibility profiles to in-depth porosity, radial stress and elastic recovery analysis. The lab can guide partners through the full R&D and production process.

Along with STYL’One EVO and STYL’One Nano, which can perform advanced software-supported testing, the laboratory houses a full range of leading-edge measuring equipment, including:

• a gas pycnometer for true density testing, laser particle sizing and morphology assessment.
• a semi-automatic SOTAX SmartTest 50 for tablet property testing and data inputs.
• a small volume Caleva mini coater and multi-head Quadro SLS for modelling milling and processing solutions that can be directly transferred from lab to the production-scale equipment.

The lab environment is fully temperature and humidity adjusted, supporting lowered hygrometry for specific needs like effervescent tablets.

MEDELPHARM Distribution

MEDELPHARM distributes for France and Belgium renowned and innovative technologies in powder processing from lab scale to production, in association with partners worldwide, primarily KORSCH AG with its internationally renowned range of rotary presses.

Other collaboration partners have included:

LB Bohle: Leading supplier of special process machines for the pharmaceutical industry Manufacturer of equipment for weighing, granulation, sieving, blending, and coating.

Caleva: Market leader in manufacturing and developing equipment for the production of pellets (beads or spheroids) by extrusion and spheronization™.

Fitzpatrick: Leading manufacturer of pharmaceutical hammer mills.

MG2: Acclaimed Capsule filling equipment specialist and packaging solution manufacturer.

Quadro: Renowned manufacturer inventor of conical mills for consistent size reduction and uniform tableting, with world-leading technologies for achieving uniform size reduction, sieving, de-agglomeration and dispersion.

ProCepT: Specialist in lab-scale R&D equipment, offering innovative solutions for drying, agglomeration, tablet coating and mixing applications, focusing on small-scale equipment.