VTU Technology’s new website unlocks Pichia toolbox

news-releasesVALIDOGEN GmbH
June 21st 2017

Grambach, Austria: Protein expression specialist VTU Technology has launched a re-engineered website that showcases multiple elements of its world-leading Pichia pastoris recombinant expression technology and protein production toolbox.

The redesigned VTU site allows browsers to explore key aspects of the Pichia toolbox, including VTU’s core technology of exclusive AOX1 promoter libraries for fine-tuned methanol-inducible or methanol-free protein production.

Building on Pichia´s inherent potential, VTU has established an exclusive yield-enhancing protein production platform that stands out from competitors in respect of diversity of expression tools and expression strategies.

Fine-tuned protein expression

The site now explains how VTU is able to unlock and boost protein production of fully active, high quality proteins.

Diversity of application is enhanced through proprietary expression techniques that enhance co-expression helper factors, further fine tuned by VTU´s promoter library to enhance product yields and quality.

Combined with high-throughput combinatorial cultivation and screening techniques, VTU is able rapidly and reliably to identify and generate high-level production strains meeting protein quality and productivity requirements.

Glycoengineering tools & half-life extension

The website also explores VTU’s glycoengineering tools that enable homogenous glycoprotein production through Pichia Glycoswitch® combined and boosted by VTU Pichia.

Half-life extension on biopharmaceuticals and biobetters, aided by fusion to human serum albumin(HSA) produced with VTU´s Pichia pastoris toolbox can be secreted very efficiently (5-20 g/l) resulting in reduced production costs at the same time increasing the profitability of a therapeutic product and maintaining quality.

The website also presents VTU’s extended portfolio of services, such as time-saving protein expression studies, comprehensive strain development, bioprocess development, protein purification & DSP development, cell banking as well as enzyme engineering.

The new site also incorporates full search function and offers more direct access to contact info, downloads and news updates, currently headed by VTU’s appearance at the upcoming BIO International Convention in San Diego, California.

About VTU Technology

VTU Technology, a leading contract research and development company, offers the broadest toolbox and most versatile technology platform available for Pichia pastoris recombinant protein expression / production enabling highest productivities delivering up to 25 g/L of secreted protein (record productivities of 35 g/L) within a few weeks development time.

VTU´s yield-enhancing Pichia pastoris expression platform is based on its proprietary AOX1 promoter libraries and set of expression enhancing helper factors, several platform strains with different genetic backgrounds, elaborated cloning and transformation protocols, a high-throughput screening and cultivation regime combined with excellent know-how in fermentation and downstream process development for maximization of product yield and overall process performance.

Headquartered in Grambach, near Graz, Austria, VTU Technology is a private company and a subsidiary of VTU Holding, an Austrian enterprise that combines several technology and engineering companies in chemistry, pharma and life science as well as in the energy industries.

More information: www.vtu.com and www.vtu.com