VTU Technology presenting Pichia production opportunities at BIO International

Grambach, Austria: Protein expression specialist VTU Technology will connect with scores of potential partners at the big BIO International Convention in San Diego next month to present unique production advantages for its innovative Pichia pastoris recombinant expression technology.

These include the use of VTU´s well-established Pichia pastoris protein production toolbox to facilitate competitive development of high-quality proteins, high-productivity strains & robust and scalable bioprocesses.

Advantage Austria

VTU will exhibit at Booth 5323 in the Advantage Austria Pavilion at the San Diego Convention Center.

“For us the BIO International Convention is one of the most important partnering events to be found anywhere in the world and a key opportunity to find collaborators for our innovative Pichia pastoris protein production technologies,” said VTU’s Head of Business Development, Thomas Purkarthofer, who will be representing the company at BIO International, along with Roland Weis, Head of Operations.

Pichia protein production toolbox

“It is also a great chance for companies from all industry sectors that need recombinant protein production technologies to discover the power of VTU´s exclusive yield-enhancing Pichia protein production toolbox with its diversity of expression tools and expression strategies”, said Dr. Purkarthofer.

“We will also be presenting our proprietary AOX1 promoter library and a portfolio of platform strains that provide the genetic diversity necessary for fine-tuning of protein expression, while timely adjusted co-expression of helper proteins allows for maximization of protein production”, said Roland Weis.

“In particular, our second generation promoter variants offer more flexibility by providing high-level methanol-free protein production processes,” he explained. “Moreover, Pichia based biologics production is no longer limited to non-glycosylated proteins. VTU additionally offers boosted glycoprotein production by combining VTU´s Pichia technology with Pichia Glycoswitch®, which enables the production of homogeneous and uniform glycoproteins.”

High-throughput microscale screening

“VTU´s unique high-throughput microscale cultivation and screening expertise and protocols allow rapid analysis of thousands of Pichia strains to ensure fast and reliable identification of the best performing genetic arrangement to produce the target protein,” Mr. Weis added.

Since foundation in 2008, VTU has been continuously optimizing and expanding its Pichia technology platform to generate an unparalleled spectrum of exclusive tools and strategies to meet highly specific expression needs, leading to more flexibility in protein production.

Short timelines

These allow VTU to addresses multiple aspects of protein expression with contract services and tailor-made solutions that combine short timelines with high flexibility. Services include time-saving protein expression studies, development of industrial production strains, process development & optimization, small-scale production of non-GMP product samples as well as cell banking and enzyme engineering services.

About VTU Technology

VTU Technology, a leading contract research and development company, offers the broadest toolbox and most versatile technology platform available for Pichia pastoris recombinant protein expression / production enabling highest productivities delivering up to 25 g/L of secreted protein (record productivities of 35 g/L) within a few weeks development time.

VTU´s yield-enhancing Pichia pastoris expression platform is based on its proprietary AOX1 promoter libraries and set of expression enhancing helper factors, several platform strains with different genetic backgrounds, elaborated cloning and transformation protocols, a high-throughput screening and cultivation regime combined with excellent know-how in fermentation and downstream process development for maximization of product yield and overall process performance.

Headquartered in Grambach, near Graz, Austria, VTU Technology is a private company and a subsidiary of VTU Holding, an Austrian enterprise that combines several technology and engineering companies in chemistry, pharma and life science as well as in the energy industries.

More information: www.vtu-technology.com and www.vtu.com

About BIO International

The BIO International Convention (BIO) provides a week of intensive networking for biotechnology and pharma leaders to discover new opportunities and promising partnerships. It attracts more than 16,000 delegates involved in a wide spectrum of life science and application areas including drug discovery, biomanufacturing, genomics, biofuels, nanotechnology and cell therapy.

BIO International 2017 is a four -day event opening June 19 at the harbor-side San Diego Convention Center in southern California. The convention will feature more than 35,000 face-to-face meetings for some 3,100 companies organised using the proprietary BIO One-on-One partnering™ system, as well as hundreds of individual company presentations, a program of world-renowned keynote speakers and some 20 Session Tracks.

A co-located trade show will feature more than 1,800 exhibitors from fields ranging from digital health and diagnostics to bioprocesses.

The event is organized by the Washington DC-based Biotechnology Innovation Organization with more information at: http://convention.bio.org/