VTU Technology brings full range Pichia protein production toolbox to CPhI Madrid

Grambach, Austria: – Protein expression specialist VTU Technology will present its enhanced Pichia pastoris protein production toolbox on its return to Europe’s largest pharmaceutical trade fair, CPhI Worldwide in Madrid in October.

VTU will exhibit at Booth 3D73 as part of the Life Science Austria stand at IFEMA, Madrid, showcasing its broadest-yet Pichia toolbox for competitive protein and glycoprotein production. The world-leading VTU Pichia pastoris recombinant expression platform offers higher efficiency production of a wide range of protein candidates for different applications.

VTU has been a consistent presence at CPhI Worldwide since 2009. Once again its CPhI team will be led by Head of Business Development Dr. Thomas Purkarthofer.

Protein productivity challenges

“CPhI provides one of the world’s best platforms to reach out to potential customers from all over the world,” commented Dr. Purkarthofer.

“Producing high-quality proteins for therapeutic applications at high yields is a crucial objective for protein manufacturers,” he noted.

“The bioprocessing industry faces many challenges in reaching its goals of increased efficiency and improved economics in protein production. Although considerable progress has been made over the past 20 years to raise the productivity and robustness of manufacturing processes for biopharmaceuticals, the cost and complexity of their development remain high,” said Dr. Purkarthofer.

Combined advantages

“From the list of therapeutic protein approvals, two pre-eminent hosts have so far dominated the field of recombinant protein expression: the bacterial Escherichia coli (E. coli) system and mammalian cell lines, such as Chinese hamster ovary (CHO) cells. Combining the advantages of these, the versatile yeast Pichia pastoris is emerging to become a competitive alternative for biomanufacturing. VTU´s Pichia system meets so far unfilled productivity needs through diversity, high productivity & product quality while maintaining flexibility & speed,” he concluded.

About VTU Technology

VTU Technology, a leading contract research and development company, offers the broadest toolbox and most versatile technology platform available for Pichia pastoris recombinant protein expression / production enabling highest productivities delivering up to 25 g/L of secreted protein (record productivities of 35 g/L) within a few weeks’ development time.

VTU´s yield-enhancing Pichia pastoris expression platform is based on its proprietary AOX1 promoter libraries and set of expression enhancing helper factors, several platform strains with different genetic backgrounds, elaborated cloning and transformation protocols, a high-throughput screening and cultivation regime combined with excellent know-how in fermentation and downstream process development for maximization of product yield and overall process performance.

Headquartered in Grambach, near Graz, Austria, VTU Technology is a private company.

More information: www.vtu-technology.com and www.vtu.com.

About CPhI Worldwide 2018

CPhI Worldwide is the flagship annual trade show for pharma ingredients and partner sourcing providing delegates and exhibitors opportunities to arrange face-to-face meetings with potential international pharmaceutical partners and collaborators and gain insights on latest industry trends.

Now in its 29th year, the 2018 event is a three-day event opening October 9 at IFEMA, Feria de Madrid, Spain, which last hosted the event in 2015. CPhI Worldwide 2018. CPhI Worldwide includes the co-located zoned exhibitions; ICSE Outsourcing solutions, P-MEC Machinery and Equipment and InnoPack pharmaceutical packaging events. Together, they are expected to attract a record 45,000 delegates along with 2,500 exhibiting companies from 153 countries.

New for 2018, the Expo will feature bioLIVE, a new specialized exhibition focusing on the biopharmaceutical industry.

The CPhI series is staged by leading Global B2B Events Organizer and Publisher UBM Live More information at: https://www.cphi.com/europe/.