VTU bringing latest technologies to Pichia 2016, Turkey and 4th BioproScale Symposium, Germany

Grambach, Austria: – Protein expression specialist VTU Technology will bring its leading expertise in Pichia pastoris recombinant technology to two scientific conferences next month.

Many industries are adopting protein production processes using Pichia pastoris for its high efficiency advantages. Rapid and reliable generation of high-level production strains, matching protein quantity and quality attributes, is key to success, particularly in biopharmaceuticals.

Pichia 2016 Antalya

VTU Technology is a platinum sponsor of the Pichia 2016 conference, opening April 3 in Antalya, Turkey. The meeting brings together Pichia players and researchers from around the globe to interact, present and learn more about the latest findings and new technology developments in the field of Pichia pastoris recombinant protein production.

VTU´s Chief Technology Officer (CTO) Dr. Roland Weis will chair the Bioprocess Optimization session on April 6, Day Three of the conference.

On the same day, from 10.45 to 11.15 a.m., VTU Technology’s Principal Scientist Process Development & Analytics, Dr. Iskandar Dib will moderate a panel discussion on production of biopharmaceuticals in Pichia with invited experts from industry and academia. The round table session will take a critical view on advantages and challenges of the Pichia system as compared to established and other emerging expression systems.

BioProScale Symposium, Berlin

Dr. Weis will also fly to Berlin to speak at the 4^th BioProScale Symposium, which opens on April 6, even as the Antalya conference winds down. The three-day event will focus on industrial scale bioprocess intensification from process development to large-scale understanding.

On the final day of the Berlin symposium, Friday April 8, Dr. Weis will present insights from VTU’s experience of high-level protein production using Pichia: including case studies showing development paths from strain generation over bioreactor.

He will show how seamless transferability of lab-scale results to more controlled bioreactor conditions is of utmost importance.

High throughput cultivation and screening

VTU’s application of a versatile promoter library for fine-tuned expression of both target genes as well as specific or general auxiliary genes creates a diversity of expression strains that can only be analyzed in depth with a solid high throughput cultivation and screening system.

Dr. Weis will showcase how VTU´s development of such a cultivation and screening system has enabled more straightforward candidate strain selection, eliminating the need for time-consuming and laborious intermediate steps like shake flask cultivation.

VTU’s high-throughput screening platform has subjected a large number of model proteins to analysis, followed by direct transfer into bioreactors, often yielding multi g/L levels of secreted recombinant protein.

Dr. Weis will disclose details of strain generation and bioreactor production procedures for selected examples including growth factors, HSA-fusion proteins as well as enzymes.

About VTU Technology

VTU Technology is a leading service provider for the fast track development of protein expression strains and protein production processes often yielding up to 25 g/L of secreted protein (recently reaching 35 g/l of secreted protein) for a wide range of biologics and other proteins. VTU Technology´s powerful Pichia pastoris protein expression technology suite, an in-house expression platform which is continuously updated and expanded, is mainly based on its exclusive AOX1 promoter libraries and complemented by its optimized gene design and cloning strategies as well as high-throughput screening and cultivation regime, combined with excellent know-how in fermentation and downstream process development.Headquartered in Grambach, near Graz, Austria, VTU Technology is a private company and a subsidiary of VTU Holding, an Austrian enterprise that combines several technology and engineering companies in pharma and life sciences, chemistry and energy.

About Pichia 2016

Pichia 2016 is the latest in a series of international conferences focusing on newest applications of Pichia pastori technology.

This four-day event opens April 6 at the Porto Bello Hotel and Resort in Antalya, Turkey.

Speakers and poster sessions will discuss the latest Pichia developments for post-translational modification, process development and the application of genome insights to improvements in productivity and look at emerging applications.

Scientific topics discussed include cell biology, protein secretion & posttranslational modification, genomic studies and genome annotations, bioprocess optimization & scale-up, molecular engineering and metabolic engineering for production of small compounds.

The Pichia series of conferences has been running since 2006, initially at three year intervals and since 2012 held every second year. Pichia 2014 was held in San Diego, California, organized by Research Corporation Technologies (RCT) and BioGrammatics, Inc.

Pichia 2016 is organized by Turkey’s Akdeniz University Food Safety and Agricultural Research Center.
More information at: http://www.pichia2016.com/en/

About BioProScale Symposium 2016

The 4^th BioProScale Symposium is an annual German conference dealing with industrial scale bioprocess intensification from process development to large-scale understanding.

The three-day English language event opens April 6 at the House of Architecture at Berlin’s Technische Universität (TU).

The 2016 symposium will focus in cross-discipline contributions for a better understanding of large-scale operation and consistency in bioprocess development, including industrial-scale bioprocess operations, scale down approaches and process analytical technologies for advanced process design and comprehensive process monitoring using non-invasive sensors.

The event is organized by TU Berlin’s Department of Bioprocess Engineering, in collaboration with the Berlin Institute for Biotechnology and Fermentation (IfGB).
More information at: http://biotechnologie.ifgb.de/front_content.php?idart=214&idcat=14&lang=4