PHCbi PrimeSurface® Cell Culture labware

PHCbi offers a range of PrimeSurface® well plates, slit well plates and dishes for 3D Cell Culture Applications.

The PrimeSurface® labware range is made from ultra-low attachment material with non-binding and non-cytotoxic surfaces to facilitate natural spheroid or EB cell formation in each well.

These high optical clarity plates facilitate spheroid assay formation and imaging analysis in the same plate and offer a variety of well bottom shapes: U-bottom, Spindle-bottom, and V-bottom in 96 well format, with 384 U-well formats also available for high throughput assays. Therefore the plates and dishes offer three different sampling capacities, from 106mL through to 300mL.

PrimeSurface® Cell Culture Plate Design and Features

PrimeSurface cell culture labware are ultra-low attachment (ULA) dishes and plates that promote scaffold free, self-assembly of spheroid formation. The plates are pre-coated with unique ultra-hydrophilic polymer that enables spontaneous spheroid formation of uniform size and shape with zero interaction with plate surface.

The widely used 96 well plates are available in a choice of U, V and M well bottom formats, giving scientists a choice to form the tighter spheroids needed for specific cell types, while 384-well U-bottomed plates support high throughput robotic systems.

The PrimeSurface® plates are designed for easy handling compatibility with liquid robotic systems.

The clear ULA plates have high optical clarity making them highly suitable for bright field imaging and confocal microscopy. They are also available as white plates, compatible with luminescent assays.

PrimeSurface® Slit Well plates

PHCbi is also offering a PrimeSurface slit-well, ultra-low attachment 3D plate to facilitate easy handling of media exchange without disrupting spheroid formation.

Cell culturing involves frequent media replacement to provide nutrition to growing cells. In a standard 96 well plate, media aspiration or dispensing has to be done extremely carefully to avoid disturbing the unattached spheroid, making this a time consuming operation.

The PrimeSurface 96 Slit-Well Plate shares the medium between wells. This interconnectedness increases by up to 50% the total amount of medium available, allowing for less frequent media changes and more nutrients for the culture. It also allows media exchange to be efficiently handled with one step dispensing or aspiration for all 96 wells, decreasing pipetting time by more than 80% while minimizing the risk of spheroid damage.

Range specifications

All plates come in radiation sterilized packages at 20 plates per case and are supplied for research or laboratory use only.

Resources

Click on PHCbi PrimeSurface Cell Culture Plates  to see product range.
Click on PHCbi PrimeSurface 96 Slit Well plate  to download product flyer.
Click on PrimeSurface Slit Well Culture Media to watch video