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    CPC Biotech releases unique Aminosniper inactivator for aminoglycoside antibiotics

    news-releasesCPC Biotech s.r.l
    September 16th 2021

    Monza Brianza, Italy: CPC Biotech, the specialist supplier of enzymes to the pharmaceutical and biotech industries, has launched Aminosniper™ as its unique solution for inactivation of aminoglycosidic antibiotics.

    Aminosniper is an enzyme-based product for the inactivation of antibiotics belonging to the aminoglycosides class that can be used as a lab reagent for verifying the sterility of products or surfaces contaminated by antibiotics belonging to the aminoglycosides class.

    Testing need

    Aminosniper addresses pharmaceutical industry need to test antibiotics before release for sterility if injectable or for bioburden in non-sterile forms.

    However the problem with setting up such tests is that the antibiotic itself can kill the microorganisms that are present in the test sample, leading to chronic underestimation of the number of organisms present in the sample.

    Pharmacopeias indicate that when a microbiological test is carry out on a sample that contains a compound that can inhibit the growth of microorganisms, as is the case with antibiotics, that  compound should be inactivated in order to avoid false results. This has been difficult in previous years with only beta-lactamases enzymes available on the market, such as CPC’s own  Lactamator™, and Penase™.

    Broad range of applications

    Freeze-dried Aminosniper™ efficiently inactivates a broad range of aminoglycoside antibiotics, including Neomycin, Tobramycin, Gentamycin and Ribostamycin.

    Available in packs of five 25IU (International Units) of amino glycosidase per vial plus five vials of diluent solution. Each IU is defined as the amount of enzyme needed to hydrolyze 1 μmole of Gentamycin sulphate per minute at 25°C and pH 7.0, for applications that include sterility testing, total count and media fill.

    Due to its very broad specificity range, AMINOSNIPER™ can also be used in the assessment of the susceptibility of new aminoglycoside antibiotics to inactivation by amino glycosidases.

    CPC breakthrough

    CPC then made an initial breakthrough Macroduster™ as a pioneering and unique enzyme for the inactivation of macrolide antibiotics.

    Now Aminosniper provides a unique solution for inactivation for the aminoglycoside class of antibiotics.

    “We are proud to be able to bring Aminosniper to market as very useful tool for the global pharma industry,” commented CPC Biotech CEO and President Fabio Arenghi.

    “While several companies offer beta-lactamase antibiotic inactivators, no one has matched CPC in also offering enzymes to inactivate macrolide and aminoglycoside antibiotics,” said Sig. Arenghi.

    “Once again we have shown that CPC Biotech is a company with the deep knowledge and technologies needed to unlock inactivation of antibiotics around the world,” he concluded.

    About CPC Biotech

    Founded in 2006, CPC Biotech srl has rapidly established a reputation as a leading producer and contract manufacturing organization that develops and supplies of enzymes for Quality Control (QC) for the pharma and biotech industries as well as ready-to-use media for microbiology.

    The company has become an internationally respected center of expertise in the specialized field of antibiotics inactivation and acts as a consultant to several world-leading pharma companies. It produces a range of enzymes able to inactivate antibiotics that are used in micro QC analysis for sterility testing and total count on antibiotics as well as in environmental monitoring of clean rooms.

    CPC Biotech was a pioneer in developing highly stable, broad-spectrum beta-lactamases and has uniquely developed an enzyme for inactivation of macrolids antibiotics. It is also distinctive in offering heparinases for QC testing of low molecular heparins like enoxaparin.

    CPC Biotech offers a range of products and services grouped into two fields; enzymes for pharmaceutical and industrial use, and biotech enzymes for pharmaceutical QC, including Lactamator™ for inactivating penicillins, Cephalosporins and Penems, Macroduster™ for macrolids inactivation and Carbamator™ for hydrolyzation and degradation of carbapenems, penicillins and cephalosporins.

    Further information at:


    Click on Aminosniper™ innovative enzyme-based product for further information

    CPC Biotech releases unique Aminosniper inactivator for aminoglycoside antibiotics

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