Continuous Manufacturing and Tablet Processing Technologies from L.B. Bohle at INTERPHEX 2026

Ennigerloh, Germany – L.B. Bohle will showcase three examples of its pharmaceutical processing technology for oral solid dose manufacturing – the QbCon® 1 continuous granulation and drying system, BFC 5 laboratory tablet coater and BTS 200 pharmaceutical sieving machine – at INTERPHEX 2026 in New York City.

Visitors to the L.B. Bohle stand at Booth 1619 will see how the company’s latest equipment supports continuous manufacturing, efficient product development and improved pharmaceutical production processes.

These three technology highlights on the L.B. Bohle stand will demonstrate advances in continuous oral solid dose manufacturing, laboratory tablet coating and pharmaceutical particle processing.

QbCon® 1 Continuous Wet Granulation and Drying System

The QbCon® 1 represents a major step forward for continuous oral solid dose production. The system combines continuous raw material dosing, twin-screw wet granulation and drying in one compact, mobile unit.

Advanced features include sophisticated material conveyance, very short residence times in the dryer, automatic exhaust filter self-cleaning and high containment. Integrated control systems increase operational flexibility while enhancing operator safety.

The QbCon® 1 is designed to deliver narrow residence-time distributions that simplify material traceability in continuous processes. This makes it easier to track material from raw ingredients through to finished tablets while supporting accelerated scale-up.

Integrated process analytics also help reduce resource consumption and shorten pharmaceutical development times.

BFC 5 Laboratory Tablet Coating System

The BFC 5 laboratory tablet coater will form the second major technology highlight on the L.B. Bohle stand.

The BFC 5 provides a compact and mobile stand-alone solution for tablet coating operations, performing spraying, mixing and drying simultaneously under tightly controlled conditions to achieve optimal coating uniformity.

Airflow management, electrical systems and process control are fully integrated, with multi-panel visualization available through an intuitive touchscreen interface.

The system is suitable for batch sizes ranging from two to 13 litres, while the mini drum enables processing of pilot batches ranging from 170 to 350 ml. This makes the BFC 5 particularly suitable for research and development as well as process optimization.

BTS 200 Pharmaceutical Sieving Machine

The third technology highlight at INTERPHEX will be the BTS 200 pharmaceutical sieving machine, demonstrating L.B. Bohle’s advanced engineering in particle processing.

The system calibrates particle size for dry or moist products and can also be used for general mixing and sieving operations at throughput rates of up to three metric tonnes per hour.

A range of optimized perforated and friction-type conical sieve inserts allows the machine to handle a wide variety of powders and pharmaceutical materials.

The latest BTS 200 design includes an innovative impeller configuration that reduces product loss, optimized CIP cleaning, electrical height adjustment and user-friendly touchscreen control.

Optional Radio Frequency Identification (RFID) transponders can also be attached to sieve inserts. These allow the process control system to automatically recognize the installed sieve, ensuring that the correct insert is used for the selected process recipe while supporting improved data collection for process optimization.

Rapid development

“Continuous manufacturing and flexible development-scale technologies are becoming increasingly important for modern oral solid dose production,” said Mike Fazio, Director, Sales & Marketingat L.B. Bohle LLC.

“At INTERPHEX 2026 we will demonstrate how our latest systems support faster development, improved process control and more efficient pharmaceutical manufacturing,” he added.

Visitors to Booth 1619 at INTERPHEX 2026 will be able to see the systems first-hand and discuss applications in continuous manufacturing, tablet coating and pharmaceutical particle processing with L.B. Bohle specialists.

About L.B. Bohle

Founded in 1981, L.B. Bohle Maschinen und Verfahren GmbH (L.B. Bohle) has established a worldwide reputation as a producer and supplier of advanced systems for pharmaceutical manufacturing, based on a track record of technological innovation and continuous improvement.

Based at Ennigerloh in Northwest Germany, L.B. Bohle operates worldwide, offering advanced solutions for every aspect of oral solid dose (OSD) and nutraceutical tablet production, including weighing & dosing, grinding & sieving, blending, tablet coating, sorting, handling systems, cleaning and containment, and continuous manufacturing.

The company’s guiding vision is one of technological innovation in the production of pharmaceutical solids. This supports a core mission to deliver maximum product efficiency increases for its customers, through continuous development and product innovations that not only increase quality and efficiency but also strengthen competitive edge and sustainability.

To these ends, L.B. Bohle offers both complete production lines and solutions for individual production steps, focusing on rapid development and production of sophisticated, pragmatic, and customized applications.

The company operates development and manufacturing facilities at its home base at Ennigerloh and at Sassenberg, both in North Rhine-Westphalia. Additionally, it has sales and service subsidiaries in the USA (Warminster, PA) in India (Ahmedabad), and Switzerland (Reiden). It is also represented by more than 40 qualified sales partners worldwide, having become a globally recognized brand.

Further information at: www.lbbohle.com  and www.continuous-manufacturing.com

About INTERPHEX 2026

For more than four decades, INTERPHEX has been one of the leading global events for biopharmaceutical and pharmaceutical manufacturing technologies.

The 46th INTERPHEX Expo will showcase a wide range of solutions for cost-effective pharmaceutical product development and manufacturing, including equipment, accessories and processing technologies.

The event also offers networking opportunities, expert presentations and live demonstrations of the latest pharmaceutical manufacturing innovations.

INTERPHEX 2026 will take place from April 21–23 at the Javits Center in New York City and is sponsored by the Parenteral Drug Association.

More information is available at: www.interphex.com

Resources

Click on Continuous Manufacturing: Machines and Processes to find out more about QbCon® technology.
Click on QbCon® 1 in action to see video.