VTU Technology to ‘unlock Pichia’ at PepTalk 2018

news-releasesVALIDOGEN GmbH
December 19th 2017

Grambach, Austria: – Protein expression specialist VTU Technology will be sharing insights on the keys to unlocking the power of Pichia pastoris-based protein expression at America’s Protein Sciences Week, PepTalk 2018, in San Diego.

VTU will be represented at the event by VTU´s CTO Roland Weis and principal scientist Iskandar Dib.

Iskandar Dib will participate in the “Engineering Genes and Hosts” stream on Day Two of the conference, Tuesday, January 9, delivering a presentation “Unlock Pichia – Novel Strategies and Molecular Tools to Enhance Protein Expression”.

Competitive with Pichia pastoris

Iskandar will introduce how VTU addresses the multiple aspects of protein expression by increasing genetic diversity. Applying its Pichia pastoris toolbox, VTU generates a large number of different genetic constellations thus unlocking Pichia´s potential for successful production of fully active, high quality proteins through fine-tuning of expression.

VTU’s extended molecular toolbox addresses challenges all the way from transcription and translation to translocation, protein folding and secretion and facilitates the expression of more complex proteins thus maximizing yields without compromising product quality.

The latest technology developments and versatile applications of VTU´s Pichia pastoris protein expression technology platform will be presented.

Dr. Iskandar Dib is a graduate of Graz University of Technology and the Research Center for Applied Biocatalysis. After obtaining his PhD he joined the team of VTU Technology where he now heads the DSP and Analytics department.

Dr. Dib’s areas of expertise include process development for up- and downstream processes applying DoE tools for process understanding. He is also responsible for VTU’s protein products, co-developed with a partner company.

About VTU Technology

VTU Technology, a leading contract research and development company, offers the broadest toolbox and most versatile technology platform available for Pichia pastoris recombinant protein expression / production enabling highest productivities delivering up to 25 g/L of secreted protein (record productivities of 35 g/L) within a few weeks development time.

VTU´s yield-enhancing Pichia pastoris expression platform is based on its proprietary AOX1 promoter libraries and set of expression enhancing helper factors, several platform strains with different genetic backgrounds, elaborated cloning and transformation protocols, a high-throughput screening and cultivation regime combined with excellent know-how in fermentation and downstream process development for maximization of product yield and overall process performance.

Headquartered in Grambach, near Graz, Austria, VTU Technology is a private company and a subsidiary of VTU Holding, an Austrian enterprise that combines several technology and engineering companies in chemistry, pharma and life science as well as in the energy industries.

More information: www.vtu-technology.com and www.vtu.com.

About PepTalk Protein Science Week 2018

PepTalk: The Protein Science Week is one of the largest annual gatherings of protein science researchers in the world. The conference attracts nearly 1,300 experts from academia, biotech and pharma who come together for one week of intensive learning and networking focusing on a wide spectrum of applied protein sciences with emphasis on upstream R&D engineering to downstream biologics production.

Now in its 17th year, PepTak 2018 is a five-day event that opens January 8, 2018 at the Hilton San Diego Bayfront Hotel & Conference Center.

The conference programs features keynote presentations, case studies and new unpublished data from top influential leaders in academia and industry, along with training seminars, dinner short courses and a co-located exhibition.

The event is organized by Cambridge HealthTalk (CHI) with more information available at: www.chi-peptalk.com