By Brinter Ltd.
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New Visco Bio medical print heads for Brinter® bioprinters minimize waste and enhance repeatability
Turku, Finland: – Pioneering modular multi-material bioprinting platform developer and manufacturer Brinter, has announced the release of new extrusion-based Visco Bio medical print heads for its Brinter® bioprinters.
The new modular print heads, developed in collaboration with ViscoTec’s Puredyne® division, almost eliminate dead volume, minimising waste of expensive medical grade materials.
The heads can be fitted to Brinter’s flagship Brinter® One modular bioprinter that is able to print multi-material and highly complex tissue structures in 3D, providing all the basic features needed for bioprinting. The device can print both stiff and soft materials, including but not limited to liquids and hydrogels with living cells, bio-paste, metal with a binder material, as well as thermoplastics.
Other benefits of the Visco Bio print heads include:
- More material diversity for dispensing, repeatability with a continuous and precise printing process
- Zero cross-contamination due to the use of a single cartridge per material.
- Advanced dispensing geometry conveying constant volume per revolution and very precise application of material
- Programmable suck-back to ensure clean start and finish points.
- Continuous and precise printing processes ensuring enhanced repeatability of printing results
Meeting GMP requirements
Brinter CEO Tomi Kalpio commented:
”On the back of a strong first year’s growth year in 2021, Brinter continues to develop and implement new features to our devices.”
“The release of this print head meets basic requirements for Good Manufacturing Practices (GMP) compliance, due to no cross-contamination with the use of a single cartridge per material, used together with the disinfecting blue light module we published in December. Likewise, researchers, pharma industry, and universities benefit from the repeatability of printing results being increased due to continuous and precise printing processes,” Mr. Kalpio noted.
“The practical applications of the technology align with Brinter’s vision to improve our quality of life by shortening and enhancing the productivity of the scientific discovery process and bio-manufacturing. This pushes forward the ambition of printing human spare parts such as hearts and kidneys, as well as more personalized treatment through cancer research and drug testing,” he concluded.
Partnership with Puredyne®
Visco Bio was launched in close collaboration with Puredyne, who provided the innovative market technology.
Puredyne’s Business Development Manager Felix Gruber said: ”Brinter is an innovative and strong partner for us, with whom we already have had a close relationship for some years. The Puredyne® print head, with its involved progressive cavity technology, enables a totally new precision in extrusion-based bioprinting. Moreover, our solution gives the operator the required process and material flexibility in the handling of low to high viscosity biomaterials.”
Founded in 2020 via partial demerger in Turku, Finland, Brinter is the manufacturer of a modular multi-material bioprinting platform scalable from manual R&D to automated production. The company works with science and bioengineering organizations to integrate 3D bioprinting into their research, manufacturing, and treatment methods. The goal is to break through current technological limitations and improve people’s quality of life.
Brinter has bootstrapped its growth since 2019, when it launched its first product, and is currently active in more than ten countries, including Germany and the UK.
Customers of the company now include bio and pharmaceutical companies like Nanoform, as well as research organizations like VTT, BEST group at the University of Glasgow, Johannes Gutenberg University of Mainz, the University of Oulu, and the University of Helsinki, whose directors are enthusiastic about the technology’s potential.
To date, Brinter has raised a total of €1.2M in funding and is currently active in more than ten countries, including the USA, Germany, India, and the UK.
For more information, visit www.brinter.com.
Puredyne® is a brand launched by German-based ViscoTec to cover its extrusion-based progressive cavity bioprinting heads.
The new Puredyne by ViscoTec brand of bioprinting printheads promises a more precise printing process than previously possible – process-safe, repeatable, and so simple that users can fully focus on their research.
The business development team behind the Puredyne brand has developed the heads to fill the gap that has previously made working in extrusion-based bioprinting difficult: between syringe extrusion by extrusion spindle, which is very accurate but requires a great deal of installation space, and pneumatic extrusion, which offers no options for retraction or control over the cleaning.
This gap is seamlessly closed by Puredyne’s compact bioprinting print head in which an integrated compressed air supply is mounted as a multi-use component on a 3D printer or bioprinter, with a stepper motor ensuring full control.
The progressive cavity technology that is key to maximum precision involves a cap reservoir that is recharged after the dispensing process with zero risk of cross-contamination.
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