MOLNÁR-INSTITUTE to showcase powerful DryLab®4 Design Space Modeling Approaches at Analytica 2024 Munich

Berlin: – Molnár-Institute for Applied Chromatography will return to Munich’s Analytica trade fair to present latest enhancements to its DryLab^®4 liquid chromatography automation and advanced modelling software, as well as insights on how to simplify and rationalize HPLC development processes.

The Molnár-Institute stand at Booth A1.234 at the Messe München will again present dynamic presentations of the DryLab® and its direct chromatographic data system (CDS) connectivity that automates multiple levels of the DryLab-AQbD-liquid chromatography workflow.

Strategic Collaborations

Molnár-Institute will send a senior team to Analytica, led by its President, Dr. Imre Molnár, and will contribute to its scientific program with a poster on ‘Unveiling Column Interchangeability in UHPLC through Multivariate Modeling’. This work summarizes a full-scale investigation accomplished together with strategic academia and industry partners.

In particular, the poster presentation introduces an actual case study on European Pharmacopeia impurity analysis as a vehicle for exploring the frontier of column selection in liquid chromatography, where current platforms often fall short, failing to provide the granularity needed for precise stationary phase equivalence and optimal running conditions.

Reimagining Interchangeable Stationary Phases

This work has also seen recently published in Journal of Chromatography demonstrating how a more robust approach can be constructed based on Analytical Design Space Modeling principles to design a new method with potential to be used for LC separations across a broad spectrum of applications, including small and large molecules and in biomolecule separation.

The method uses a cutting-edge systematic modeling workflow to dissect separations within 3D Design Spaces constructed in DryLab^®4 to reveal interchangeable columns under shared methodological conditions and highlight unexpected disparities.

The study not only showcases the power of hybrid modeling approaches in demystifying complex separations but also sets the stage for a new era of efficiency and flexibility in chromatographic column selection.

About MOLNÁR-INSTITUTE

Founded in 1981, Molnár-Institute develops DryLab®4, a software for UHPLC modelling for a world-wide market. Its powerful modules gradient editor, peak tracking, automation, robustness and Design Space Comparison allow for the most sophisticated method development as required across modern pharma industries. Analytical scientists use DryLab®4 to understand chromatographic interactions, to reduce analysis time, to increase robustness, and to conform to Analytical Quality by Design (AQbD) principles, according to the recently published ICH Q14 regulatory framework.

The Molnár-Institute is a registered partner of the US-FDA, CDC and many other regulatory bodies. DryLab®4 pioneered AQbD long before regulatory agencies across the world encouraged such submissions. Widely implemented by thought leaders, the software contributes substantially to the paradigm shift towards a science and risk driven perspective on HPLC Quality Control and Assurance.

Further information at: http://www.molnar-institute.com/

About Analytica 2024

The 29th International Trade Fair for Laboratory Technology, Analysis, Biotechnology and Analytica, or analytica 2024, is one of the world’s leading summits for state-of-the-art laboratory technology and biotechnology. This biennial combined trade fair and conference covers a wide range of subjects connected with laboratory process and technology in breadth and depth.

Analytica 2024 is a four-day event opening April 9 at the Messe München Center, where it has been held every second year since 1968. Organizers are projecting more than 35,500 visitors, along with almost 1,200 exhibitors from 47 countries. For the first time, analytica will be held in combination with ceramitec, the world’s leading trade fair for the ceramics industry.

The event includes the analytica conference in the nearby International Congress Center, attracting some 1,600 delegates and featuring more than 300 lectures and speakers over three days.

Supporting program includes the analytica Forum, Finance Day, Job Day, analytica Research Award and Live Labs demonstration sessions.

Messe München International (MMI) organizes the event with more information at: https://www.analytica.de/en/

Resources

Click on Molnár-Institute at Analytica 2024 for exhibitor profile.
Click on Molnár-Institute DryLab Empower Automation Module  for product detail.