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    MOLNÁR-INSTITUTE to highlight impact of computer modelling on separation sciences at Balaton Symposium

    news-releasesMolnár-Institute for applied chromatography
    September 1st 2023

    Berlin: – The Molnár-Institute for Applied Chromatography will again be a high-profile presence at September’s Balaton Symposium on High Performance Separation Methods in Hungary, returning after a three-year hiatus.

    The Institute is a Silver Sponsor of the event and will contribute to the scientific program with an oral presentation from its President, Dr. Imre Molnár. This will highlight new regulatory updates and how Analytical Design Space model solutions, such as the Institute’s Modeling Platform can answer to emerging needs for speed, precision, and adaptability of analytical methods.

    HPLC modelling since 1986

    Dr. Molnár’s presentation, ‘Recent developments in HPLC modelling’, will give a short historical overview of how innovative software solutions have been supporting the pharma industry, ever since 1986.

    He will discuss the initial focus on isocratic separations, the subsequent extension to gradient methods in Reversed Phase Chromatography (RPC), Ion-Exchange Chromatography (IEC), and recent advancements including HILIC, HIC, SFC, and the modeling and assessment of an analytical procedure’s robustness.

    The presented modeling examples will show key advantages of a streamlined high-performance liquid chromatography (HPLC) method development process. Following such a model-assisted development workflow, allows for direct data contextualization and informed, science-based decision-making, improving analytical outcomes and creating error-proof methods that save time and resources.

    Modeling separations in seconds

    Dr. Molnár will show how ever more sophisticated techniques increasingly need in-silico experimental IT-support to measure peak positioning, depending on pH, temperature, gradient time, salt- or additive concentration and other relevant parameters. From the measured data, a software application like DryLabâ4 can reduce the time needed to model a separation across a wide range of variable conditions from many hours to only a few seconds.

    Dr. Molnár will also demonstrate the reliability and reproducibility of results achieved using 2D and 3D modeling of chromatographic separations, enabling quicker drug development and faster market-entry of new, more efficient drugs.


    Founded in 1981, Molnár-Institute develops DryLab®4, a software for UHPLC modelling for a world-wide market. Its powerful modules gradient editor, peak tracking, automation, robustness and Design Space Comparison allow for the most sophisticated method development as required across modern pharma industries. Analytical scientists use DryLab®4 to understand chromatographic interactions, to reduce analysis time, to increase robustness, and to conform to Analytical Quality by Design (AQbD) principles, according to the recently published ICH Q14 regulatory framework.

    The Molnár-Institute is a registered partner of the US-FDA, CDC and many other regulatory bodies. DryLab®4 pioneered AQbD long before regulatory agencies across the world encouraged such submissions. Widely implemented by thought leaders, the software contributes substantially to the paradigm shift towards a science and risk driven perspective on HPLC Quality Control and Assurance.

    Further information at:

    About Balaton Symposium on High-Performance Separation

    Founded in 1995, the Balaton Symposia on High-Performance Separation have become a leading event for separation sciences.

    Organized by the Hungarian Society for Separation Sciences (HSSS), the conference brings together international separation scientists and associates to the latest and most important advances in different areas of separations sciences, including GC, UHPLC, HPLC, SFC, HPCE, MS and variations, with numerous applications to small molecule, pharmaceuticals, biopharmaceuticals, and other research fields.

    The 13th Balaton Symposium is a three-day event opening September 4, returning to the Hotel Azúr in Siófok, Hungary. This is a biennial event, that was last staged as an actual meeting in 2019, replaced by the METT25 Anniversary Symposium, also in Siófok, for 2021.

    The scientific program covers all aspects of separation sciences in liquid, gas, and supercritical fluid phases as well as hyphenation with advanced detection technologies, including fundamental chromatographic separations and detection principles, methodological and technological advances including separation materials, column technologies and instruments. The 2023 symposium will place special emphasis on new developments in pharmaceutical, environmental, biomedical, forensic, life sciences and industrial separation methods.

    Celebrating separation scientists, the opening ceremony will see the Halász Medal and the Csaba Horváth Memorial prize awarded, along with the Ervin sz. Kováts Award for Young Scientists honoring an outstanding PhD dissertation.

    The event is organized by HSSS, with further information at:


    Click on Molnár-Institute Method Development Services for other information.


    Analytical Method Development: Workflow, Advantages and Future developments

    MOLNÁR-INSTITUTE to highlight impact of computer modelling on separation sciences at Balaton Symposium

    Symposium venue: Hotel Azúr in Siófok, near Lake Balaton, Hungary.

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