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    Compaction Blend M from MEGGLE – Powder mixture for technical applications

    products-servicesMEGGLE Excipients
    August 15th 2024

    Pharmaceutical Excipients specialist MEGGLE has developed Compaction Blend M as a ready-to-use (RTU) directly compressible powder mixture.

    Compaction Blend M provides an ideal solution for easing and accelerating trial batch and technical placebo tablet production, tableting demonstrations, tablet press performance testing and machine cleaning.

    Compaction Blend M features

    Compaction Blend M is presented as an odorless white powder blend of lactose monohydrate, microcrystalline cellulose, aluminum oxide, and vegetable magnesium stearate that is not intended for human consumption but ideal to use for all kind of technical applications.

    This is because it is pre-optimised for direct compression (DC) tableting with ideal properties that include:

    • Excellent flowability
    • High tablet hardness
    • High reproducibility
    • Superior homogeneity
    • Long shelf life (36 months)

    Blend M applications

    Compact Blend M is designed to provide a fast, reliable, and efficient solution to the testing and development challenges faced by companies in the pharmaceutical and dietary supplements industries. These include the need to bring new machinery online faster and more easily.

    The technical powder blend takes the guesswork out of production of trial batches (technical placebo tablets) by providing a material that is already ideally suited to a DC tableting process and needs no further optimization.

    This powder mixture is also ideal for performance tests, for example to demonstrate functions of a new tablet press for clients or customers.

    Blend M advantages

    Compaction Blend M is specifically formulated to speed up technical, testing and proving operations by removing all uncertainties regarding powder properties from the equation.

    This is particularly useful when it comes to producing trial batches of placebo tablets, etc., that are an essential part of machine validation and qualification processes. It’s also ideal for performance tests and demonstrations, providing users with greater confidence in showcasing the capabilities of a tablet press to clients and customers.

    Other tangible user benefits provided by Blend M include:

    • Speeded operations with a testing blend that’s ready for use directly from the bag
    • Smoother and more consistent tablet press functions thanks to excellent flowability
    • Higher quality technical tablets with a mix optimised for Tablet Hardness
    • Greater consistency between test and trial batches due to high reproducibility
    • Uniformity in every blend with superior powder homogeneity
    • Reduced waste and lower costs thanks to a long powder shelf life

    Resources

    Click on Compaction Blend M from MEGGLE for further information.

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    Compaction Blend M from MEGGLE – Powder mixture for technical applications

    MEGGLE Compaction Blend M is ideal for technical applications in tableting such as testing and demonstrations.

    Compaction Blend M from MEGGLE – Powder mixture for technical applications

    Compaction profile of MEGGLE Blend M shows a linear relationship between compaction forces and tablet hardness, facilitating uncompromised use in various applications.

    Compaction Blend M from MEGGLE – Powder mixture for technical applications

    Blend M PSD profile as obtained by air-jet sieving.

    Compaction Blend M from MEGGLE – Powder mixture for technical applications

    Blend M additional parameters.

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