Bachem webinar on reducing solvent consumption with PEC Peptide Easy Clean

Bubendorf, Switzerland: – The leading CDMO for peptides and oligonucleotides manufacturing, Bachem’s latest online webinar will focus on reducing the enormous quantities of organic solvents and toxic reagents consumed in developing and producing peptide-based drugs.

The main use of the reagents is to safeguard peptide production processes against nitrosamine contaminations, for which Bachem can now offer an alternative solution.

The webinar ‘Reducing solvent consumption with Peptide Easy Clean’ will show how ‘catch-and-release’ methods, like Belyntic’s Peptide Easy Clean (PEC) technology, can significantly improve the ecological footprint of the entire operation.

PEC advantages

From high-throughput to large-scale projects, PEC combines green solid-phase peptide synthesis (SPPS) with a precipitation-free workup and a low solvent-consuming purification method to enable an environmentally superior solution. This webinar highlights the current advancements in this field, showcasing industry examples like green Bivalirudin manufacturing.

The event will be hosted online via the Zoom platform on September 22, 2022,  commencing at 1730 hrs. EDT (UTC +2) and lasting approximately one hour. Registration for the event is free of charge and can be completed online (see Resources).

Expert hosts

The session will be hosted by Dr. Gavin T. Noble, process optimization chemist at Bachem UK St Helens, who has played a leading role at Bachem in the investigation of the Peptide Easy Clean platform. Prior to Bachem, Dr. Noble was a post-doctoral fellow at The University of Notre Dame (USA), researching peptide-targeted liposome nanoparticles for cancer and antimalarial therapies. He obtained his Ph.D. from the University of Manchester (UK). He has published several peer-reviewed articles in high impact journals during both his academic studies and career at Bachem.

Co-host will be Dr. Robert Zitterbart, co-Founder and Head of R&D at Belyntic GmbH, Berlin, with a particular role in developing linker systems to purify and modify peptides. Dr. Zitterbart has almost a decade of experience in the development of peptide purification technologies. After his diploma at the University of California, Berkeley, he earned his Ph.D. at Humboldt-University, Berlin. During his scientific career, Robert has successfully published many articles in peer reviewed journals.

The webinar will also hear from Dr. Dominik Sarma, Belyntic’s director of marketing and quality, who co-founded the company in 2018, along with Dr. Zitterbart, Oliver Reimann, and Andreas Regnery. Dr. Sarma’s Ph.D. is in advanced analytical materials at the Humboldt-University Berlin, and he played an influential role in Belyntic’s development of PEC as a first universally applicable, cleavable linker for catch-and-release peptide purification and modification.

About Bachem

Bachem is a leading, innovation-driven company specializing in the development and manufacture of peptides and oligonucleotides.

With over 50 years of experience and expertise Bachem provides products for research, clinical development and commercial application to pharmaceutical and biotechnology companies worldwide and offers a comprehensive range of services.

Bachem operates internationally with headquarters in Switzerland and locations in Europe, the US and Asia. The company is listed on the SIX Swiss Exchange.

For further information, see www.bachem.com.

Resources

Click on Bachem webinar ‘Reducing solvent consumption with Peptide Easy Clean’ to register for the event.
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