Gasporox introduces LineArch™ as breakthrough stand-alone CCIT testing solution

Lund, Sweden: – Non-destructive testing technology specialist Gasporox AB has taken a significant step forward with the launch of LineArch™ – its first fully packaged industrial headspace gas-testing solution.

As a standalone, plug-and-play platform, LineArch provides the pharmaceutical industry with a fast and accessible way to integrate GMP- and USP <1207>-compliant non-destructive container closure integrity testing (CCIT) into existing filling and packaging lines.

All-in-one solution

LineArch is a self-contained module designed for installation alongside existing or new production lines. The system is built around a compact cabinet that houses the DC power supply and electrical connections, as well as RS422 serial, USB, and digital optical I/O ports for optional data-communication interfaces.

The cabinet supports an intuitive touchscreen control panel and can be fitted with a wide range of VialArch™ or BottleArch™ inspection modules. These modules use Gasporox TDLAS (tuneable diode laser absorption spectroscopy) to deliver instant, non-intrusive measurement of oxygen, carbon dioxide, or H₂O determined pressure levels in the headspace of sealed vials, ampoules, or larger bottles. The unit can also be equipped with an eject system to automatically remove non-compliant containers from the line.

Instant integration

Roland Koch, Gasporox Director of Sales & Applications, commented:

“We are responding to a frequently expressed customer wish: to make it easier to integrate our VialArch and BottleArch sensors into production lines without requiring third-party engineering or in-house machine-building expertise.”

He added:

“Previously, we offered these sensors only as discrete modules that required additional light engineering to mount and connect them. With LineArch, we have gone much further — creating a full ‘light machine’ that simplifies integration of TDLAS technology directly into the production environment.”

CCIT and HSA needs

Gasporox has highlighted the growing need across pharmaceutical manufacturing to adopt in-line CCIT and headspace analysis (HSA) to avoid multimillion-euro losses associated with late detection of container-quality issues. Traditional QC approaches still rely on manual deterministic sampling, inspecting only a small subset of containers and providing no real-time process feedback. When sealing or closure defects are detected only after production is complete, manufacturers face unnecessary waste, compliance risks, and substantial financial impact.

“LineArch solves these problems with a simple and easy plug-and-play machine for in-line headspace analysis, without the large-scale engineering projects currently required for sensor integration,” Mr. Koch explained.

“It fits easily into new lines and can be retrofitted onto older ones, enabling process improvement with minimal downtime or redesign. It is almost in a class of its own in providing an in-line headspace analysis system that simply needs to be placed beside an existing line—dramatically lowering the barrier to moving from batch/sample testing to 100% in-line inspection.”

Practical quality upgrade

LineArch supports deterministic CCIT in accordance with USP <1207>, helping manufacturers improve compliance and reduce the risk of recalls. It provides fast, accurate, and fully non-destructive headspace analysis that integrates seamlessly into existing production lines with minimal setup.

Its compact footprint, self-calibrating functions, low maintenance demands, and compatibility with both small and large parenteral formats make LineArch an ideal QA upgrade for small to mid-sized pharmaceutical manufacturers.

Thanks to automatic triggering, the only parameters that must be pre-programmed into the LineArch operating system are container diameter and belt speed, both entered via the onboard touchscreen or a connected computer.

Gasporox has been developing LineArch for almost a year and showcased a non-functional prototype at the most recent CPHI Worldwide in Frankfurt. The system is now in full production and available to order.

About Gasporox

Gasporox, based in Lund in southern Sweden, develops and manufactures laser-based sensors for integration into in-line inspection and production lines for Headspace Analysis and Leak Detection. Gasporox sensors are also available in various instruments ideal for quality control and at-line inspection of packaging and support many different package formats as highly effective tools for more efficient sample testing and greener production.

The VialArch™ is a unique laser-based solution for vials to be installed on the production line for 100% quality inspection for residual oxygen and container closure integrity testing. The laser beam is passing the headspace of the moving vials to perform laser-based headspace analysis (HSA), non-destructive and with precise measurements of the residual oxygen in the headspace.

The GPX1500 Film Pharma is a compact and easy to use instrument to measure accurate the headspace of pharmaceutical bags and pouches. It’s designed to operate parameter free to have a reliable and accurate use in the pharmaceutical production and lab. The GPX1500 Vial is the Film Pharma’s sibling for rigid containers, like vials and ampoules.

The available Headspace Analysis sensors work with many types of containers like vials, ampoules, bottles, bags and trays and are available for measuring O2, CO2, H2O, or the pressure inside the inspected container and are suitable for Leak Detection on packages like trays, bags. These sensors can be integrated into production machines or form the basis for stand-alone instruments.

Gasporox technology has been proven for performance and robustness over more than a decade in the pharmaceutical industry in the testing of parenteral drugs. It is integrated and used in machines, systems and instruments for total lab and production testing of vials and ampoules in many parenteral packaging lines.

Gasporox testing technologies are non-destructive and deterministic and recommended by <USP1207>.

Learn more at: www.gasporox.com

Resources

Click on LineArch In-Line Machine for CCIT and HSA of pharmaceutical parenterals to learn more.