By enGenes Biotech…
enGenes Biotech introduces eXrase® as DNA cleaver and cleaner
Vienna, Austria: – Recombinant protein specialist CDMO enGenes Biotech has introduced eXrase®, a high-quality and cost-effective recombinant endonuclease for cleaving RNA and DNA and efficiently removing DNA residues.
enGenes eXrase® is the latest of a family of products based on the patented -eXpress™ recombinant protein expression platform. enGenes -eXpress™ technology allows eXrase® to efficiently degrade all forms of DNA, ensuring the effective removal of DNA residues from products derived from microorganisms.
Research and industrial applications
Available as an industrial-strength commercial product, eXrase® is offered through the BIOSYNTH portal in research and technical-grade variants. This highly efficient endonuclease provides a reliable and cost-effective solution for degrading DNA and RNA, supporting diverse applications in biotechnology, pharmaceuticals, and food production.
This versatile enzyme meets critical demands in industrial workflows, enhancing the purity of biopharmaceuticals and improving the quality of food and feed production.
Now available in industrial quantities at highly competitive pricing, eXrase® empowers manufacturers to streamline their production processes while maintaining the highest standards of quality.
Accessible Excellence
enGenes Biotech CEO and founder Dr. Jürgen Mairhofer commented: “At enGenes Biotech, we are committed to advancing biotechnology by delivering solutions that balance innovation, quality, and accessibility.”
He said -eXrase® exemplified this approach by offering a robust and efficient endonuclease with additional power provided by enGenes’ proprietary -eXpress™ technology.
“With its unparalleled combination of performance and affordability, eXrase addresses the growing demands of modern bioprocessing while enabling our customers to achieve more with less. This product is a significant step in our mission to set new standards in biotechnological excellence,” said Dr. Mairhofer.
Dr. Patrick Stargardt, Product Manager, added: “eXrase® offers an exceptional combination of efficiency, quality, and affordability. It is the ideal tool for applications where removing DNA residues is critical, supporting a wide range of industrial processes, from biopharmaceutical production to enzyme manufacturing. Moreover, its effectiveness in large-scale fermentation applications, such as reducing viscosity, ensures smoother downstream processing and improved operational efficiency. This versatility makes eXrase a valuable asset for industries aiming to optimize their workflows and enhance product quality.”
Future Applications
Building on its proven effectiveness, eXrase® has the potential to address broader industrial challenges, offering versatile solutions in multiple applications, such as:
• Industrial Cleaning and Hygiene: In industries such as food production and pharmaceuticals, eXrase® can simplify cleaning processes by efficiently removing DNA residues and disrupting biofilms on surfaces. This makes it a valuable tool for maintaining stringent hygiene standards and enhancing operational efficiency.
• Revolutionizing Detergent Technology: The enzyme is also poised to transform washing powders and detergents, with more precise targeting of nucleic-acid-rich stains such as blood and sweat. By incorporating eXrase®, manufacturers can offer advanced cleaning solutions that not only tackle stubborn stains but also prevent biofilm buildup in washing drums, ensuring a deeper clean and prolonged machine life.
• Niche Cosmetic Applications: While still in its exploratory phase, eXrase® holds promise for niche applications in the cosmetics industry. Its ability to enhance purity could inspire innovations in high-performance skincare, potentially setting new benchmarks for product quality and effectiveness.
About enGenes Biotech
enGenes Biotech GmbH (enGenes) is a contract research, development and manufacturing company that provides leading-edge technologies and production services focused on recombinant proteins in bacteria. The company’s mission is to provide cost-effective and scalable production of recombinant proteins at a fraction of the current cost, allied to a vision of developing a world-class portfolio of cutting-edge protein production technologies, relevant to a broad spectrum of application fields.
enGenes has developed advanced technologies to drive more cost-effective recombinant protein production processes, including its proprietary enGenes -eXpress™ E. coli platform that achieves outstanding yields of soluble and active recombinant protein. enGenes- eXpress™ has been successfully applied for the manufacturing of enzymes and biopharmaceutical products that failed to give economically feasible yields in a conventional expression host.
enGenes Biotech offers development and manufacturing services tailored to the needs of pharmaceutical and industrial biotech companies. The services include expression strain and vector development, fermentation process development and optimization, downstream process development, production of purified protein, technology transfer and scale-up support with technology out-licensing and co-development opportunities.
Find out more at: https://www.engenes.cc
Resources
Click on enGenes -eXrase DNA Endonuclease, tech-grade for detailed product information.
Click on enGenes -eXrase DNA Endonuclease, research-grade for detailed product information.
Click on Introducing the Most Cost-Effective DNA Endonuclease on the Market for BIOSYNTH presentation.