Key Factors Influencing Measured Tablet Hardness

white-paperDr. Schleuniger Pharmatron
June 29th 2012

ABSTRACT

Measuring tablet hardness (breaking force) plays a vital role in defining dosage form with optimum physical characteristics and testing whether produced dosage form meets the defined specifications in manufacturing. Testing tablet hardness is more than ensuring the mechanical integrity of produced tablets during subsequent processes. Because the hardness of a tabletdirectly relates to all other physical parameters, it is a fast and efficient test that indicates whether specifications such as disintegration time and friability will be met. It is therefore essential, that hardness measurement is done correctly – and that the equipment used to test tablet hardness guarantees repeatable results.

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Key Factors Influencing Measured Tablet Hardness