In vitro assays: proliferation and apoptosis
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The Pharmatest in vitro proliferation assay has been designed to measure the ability of cancer drug candidates to inhibit proliferation of several cancer cell lines. This assay is a rapid and reliable screening-type assay for cancer drug discovery.
A WST-1 based proliferation assay is used to assess cell viability and proliferation.
Further information on the mechanism can be obtained by measuring caspase 3/7 activation as an index of apoptotic (programmed) cell death.