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Evercyte hosting Altertox Training Workshop on GCCP in Toxicology

news-releasesEvercyte GmbH
October 17th 2018

Vienna, Austria: – Innovative biotech manufacturer Evercyte will host a training workshop on Good Cell Culture Practice (GCCP) in Toxicology as part of the Europe-wide Altertox Academy program.

The two-day workshop will take place at the end of October, located at Evercyte’s laboratories in Vienna, to be hosted by co-founder and Chief Technology Officer, Dr. Regina Grillari.

Evercyte is renowned for its expertise in human telomerized cells and its abilities to produce high quality cells that comply with Good Cell Culture Practice (GCCP) standards. Its expanded range of services now includes assay development, cell line development and non-invasive generation of induced pluripotent stem cells (iPSCs) from human urine.

Humanized relevant cell models

The workshop aims at toxicologists of all levels of experience and seniority from industry, CROs and research organizations for whom availability of highly humanized, relevant and standardized in vitro model systems are a prime concern.

The course will cover various aspects of good cell culture practice in toxicology and cell cultivation including optimizing cell culture for telomerized endothelial cells (angiogenesis cell model), wound healing assay using keratinocytes, thawing and culturing of iPS cell-derived neural stem cells, practical work with assay ready cells and study of cellular responses.

Angiogenesis-based in vitro toxicology

Head of cell line development at Evercyte, Dr. Matthias Wieser will demonstrate the relevance of angiogenesis cell models in the hands-on training session “Angiogenesis in in vitro toxicology – standardized cell systems”. He will also lead a session on “Telomerized cells for the development of relevant and standardizable in vitro toxicity assays”

Other sessions will be hosted by partner organizations including Upcyte, Axol Biosciences, acCELLerate, Promega and ECVAM.

“This will very much be hands-on-training delivered by experts for professionals”, said Dr. Regina Grillari.

“Evercyte has wide and deep involvement in GCCP in toxicology that we look forward to sharing with a Europe-wide community, in partnership with Altertox Academy,” she added.

About Evercyte

Evercyte GmbH, based in Vienna, manufactures a range of innovative cell-based products; telomerase (hTERT) immortalized or life span extended cells and differentiated cells from immortalized or normal stem cells.

Recently, Evercyte has become a key player in the development of induced pluripotent stem (iPS) cells from human urine as a non-invasive source for generating cell material. The company also offers a range of cell-based assays, used in development of drug screening strategies and other applications. It also develops assays to individual specification to help customers reduce their time and spend on drug discovery and development.

Evercyte’s Pharmacocellomics™ is also improving the predictability of substance efficiencies and side effects in the general population by systematically establishing and commercializing relevant cell type specific model systems from donors of different genetic backgrounds.

About Altertox Academy GCCP Workshop

The Belgian-based Altertox Academy connects international experts to provide hands-on-training in human-relevant alternative methods and technologies for toxicologists of all levels of experience and seniority. The Academy aims to empower participants with new technologies, making them familiar with critical steps not usually described in OECD Test Guidelines.

The Academy provides a platform for two-day training workshops hosted across Europe by sponsoring academic or industrial organizations with expertise in specific fields. Certificates are provided at the end of each training that provide qualifications for further education for ERT and ISO attribution.

The Evercyte-sponsored Altertox Workshop on Good Cell Culture Practice (GCCP) in Toxicology opens October 30 at Evercyte’s Vienna headquarters, with the company’s co-founder Dr. Regina Grillari as lead instructor.

The course will cover influence of culture conditions and age on cell performance, a standardized system set-up on angiogenisis in in vitro toxicology (primary vs. immortalized cell lines), preparation of spheroids and more. Trainers will be drawn from Evercyte, acCELLerate, Promega, Axol Bioscience and Upcyte.

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