Distinguishing GMP and GLP Washing Needs

Prata di Pordenone, Italy: – The latest blog post from leading pharma process equipment supplier LAST Technology clarifies the different washing requirements for Good Manufacturing Practice (GMP) and Good Laboratory Practice (GLP).

In both areas, washing equipment forms an essential part of the development and production processes, ensuring that the tools and equipment used are free of contaminants and meet the quality standards required by international regulations.

However, the detailed regulatory requirements and equipment needs for GLP applications are different from those that apply to GMP processes.

Matching equipment with application

The blog post explains how and why GMP and GLP washing equipment needs different characteristics in design, flow rate regulations, documentation, and process automation.

It explains key differences such as:

• Mechanical design and flow rate regulations
• The need for full draining of GMP washers that does not apply to lab equipment
• Different specifications for seals, connections and piping
• Documentation: with GMP qualification requiring documentation to GAMP 5 standards
• Different software, automation and process control requirements

Correct choices

The blog observes that making the correct selection of washing equipment can significantly affect efficiency, safety, and quality in both production and research, but that the choice cannot be guided by machine specifications alone. Rather, it is a question of matching equipment with individual customer requirements and circumstances.

Selection must also consider factors such as the type of materials to be washed and integration with other production processes.

“Opting for the most appropriate washing equipment is essential to ensure maximum operational efficiency, personnel safety and regulatory compliance, thus contributing to the success of both pharmaceutical and laboratory operations. At LAST Technology we offer our advice, even before our machines, to help you make the best choice” the post concludes.

About LAST Technology

Founded in 2012 and based in far northeastern Italy, LAST Technology s.r.l. has taken little more than a decade to establish itself as a leading provider of highly advanced and cost-effective process equipment for the pharma, biotech, medical research, and other industries.

LAST Technology specializes in highly tailored end-to-end washing, disinfection, sterilization, depyrogenation, decontamination, and containment solutions adapted to individual customer needs, with tailored machines whose design recognizes all aspects of the product life cycle, from prototype to product launch and validation.

Its Lab Division specializes in providing cGLP process equipment for research and microbiological laboratories, including washing, decontamination, disinfection and sterilization equipment, while Pharma Division focuses on cGMP process machinery for pharmaceutical and biotechnology manufacturing, including UCW machines for washing, disinfection and drying, RSA Autoclaves, TS-AS and TS-OW Terminal Sterilizers, DHS Dry Heat Sterilizers, DPB Decontamination Pass Box equipment, and CPE and CPE-W Closure Processing Equipment for end-to-end container processing.

LAST solutions are given added value by high levels of quality, reliability and sustainability, reflected in design for reduced energy consumption and footprint, engineering based on easily obtainable commercial components, integration with Industry 4.0 Manufacturing Execution System (MES) principles, extensive GMP and GAMP5 documentation, FDA 21 CFR, Part 11 data integrity, and extensive technical support.

Learn more at: https://lasttechnology.it/en/

Resources

Click on  What are the differences between GMP and GLP washing equipment? to read the full LAST Technology blog post.
Click on LAST Technology Blogs and News for further information.