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UGA Biopharma partners with Tosoh Bioscience on cell line and USP technology transfer to generate new DSP knowledge
Hennigsdorf, Germany: UGA Biopharma GmbH (UGA), the leading-edge contract development and research organization for biologics and biosimilars, has entered a partnership with US-based Tosoh Bioscience LLC to exchange knowledge on upstream and downstream bioprocessing (USP/DSP) of UGA´s ready-to-use biosimilar cell lines. The partnership, which took effect September 1, 2021, will leverage the two companies’ respective strengths to develop and optimize the bioproduction of UGA’s cell lines.
Tosoh Bioscience will have access to UGA’s library of ready-to-use biosimilar cell lines for its newly created cell culture laboratory in King of Prussia, PA. UGA’s portfolio of cell lines will enable Tosoh Bioscience to express a wide range of mAbs, fusion proteins, and enzymes for biopurification and bioseparation research and applications development. UGA intends to transfer its know-how on upstream development to Tosoh Bioscience and share its knowledge on cell line development. By harnessing UGA’s expertise, Tosoh Bioscience will be able to produce its own biological feedstocks at its King of Prussia facility for internal projects and use.
In return, Tosoh Bioscience’s chromatography experts will develop robust and innovative methods for the purification and characterization of the feedstocks. Through this development process, the company will utilize its latest technologies in process chromatography resins and bioanalytical techniques. UGA plans to make these methods available to its customers. Tosoh Bioscience and UGA plan on presenting the results of the collaboration through various publications, conferences, and other outlets.
About UGA Biopharma
UGA Biopharma GmbH is an experienced contract research and development organization of biologics and biosimilars with the capabilities to handle all necessary steps from cell line development and bioprocess development to the development of purification strategies and appropriate analytics.
The company supplies its customers in Germany and abroad from its headquarter in Hennigsdorf, near Berlin. Several clients have used UGA products in clinical trials or in products that have received market authorization.
UGA Biopharma GmbH CRDO activities are centered on cell line development for biologics and biosimilars, specializing in the development of stable expressing CHO cell lines and cell media for the production of biologics and biosimilars for biopharmaceutical companies. Typical clients are biopharma manufacturers, research institutions (like universities and research institutes) as well as start-ups and other CROs that need to outsource CLD, upstream, and/or downstream processing.
UGA’s mission is to fulfill customer requests, recognizing industry needs for high titer, high quality and fast delivery timelines, along with robust CHO cell lines. To this end, UGA can deliver cell lines, reaching titers from 4 to 7 g/L, within four months of receiving the originator sequence.
UGA has also developed its proprietary First CHOice® cell culture media and feeds platform to boost the productivity of cell lines. Furthermore, UGA Biopharma GmbH offers ready-to-use biosimilar cell lines, which allow clients interested in biosimilar development fast track access to a highly biosimilar cell line.
Further information at: www.ugabiopharma.com.
About Tosoh Bioscience
Tosoh Bioscience LLC provides liquid chromatography products to laboratories and manufacturing plants in the Americas. While the majority of our customers work in biotechnology and pharmaceutical companies, our U/HPLC columns and systems are essential tools for sample analysis in most industries. The LenS®3 Multi-Angle Light Scattering Detector offers a revolutionary approach for the measurement of molecular weight (MW) and radius of gyration (Rg) of synthetic polymers, polysaccharides, proteins, and biopolymers. Our all-in-one dedicated GPC system, the EcoSEC® GPC System, is predominantly used in the chemical and polymer industries while our EcoSEC High Temperature GPC System is ideal for the polyolefin and oil industries. In the field of biotechnology, our preparative chromatography resins play a critical role in the purification of proteins and nucleic acids for medical purposes.
The company is a subsidiary of Tosoh Corporation in Japan, the parent of the Tosoh Group, which comprises over 100 companies worldwide and a multiethnic workforce of over 12,000 people and generated net sales of ¥732.9 billion (US $6.9 billion at the average rate of ¥106.1 to the US dollar) in fiscal 2021, ended March 31, 2021. Tosoh’s Bioscience Division comprises products and solutions of both separation and purification and of clinical diagnostics serving customers worldwide.
“Tosoh Bioscience” and “EcoSEC” are the registered trademarks of Tosoh Corporation in Japan, the United States, and other countries/territories. “LenS” is a registered trademark of Tosoh Bioscience LLC in the USA, India and Japan.
Further information at: https://www.tosohbioscience.com
Click on UGA Biopharma First CHOice Medium and Feeds for more information.