State of the Art Bioinformatics

Bioinformatic data analysis is an important task in next generation sequencing projects, because NGS generates huge quantities of data. Vertis can provide help to clients by employing state of the art bioinformatics to extract maximum information from their experiments. Vertis uses of the CLC Bio Genomics Workbench software package, which incorporates cutting-edge technology and algorithms.

The bioinformatics service covers the following tasks:

Trimming of Reads

• Barcode filtering of reads
• Quality trimming of raw sequence data

Mapping and Clustering of Reads

• De-nova assembly of reads
• Mapping of reads to reference genomes

RNA-Seq Analysis

• Digital gene expression (DGE) analysis
• Discovery of novel exons
• Discovery of splice variants
• MicroRNA analysis
• BLAST analysis

Genome Analysis

• Identification of SNPs and DIPs (deletion/insertion polymorphisms)
• Extraction of biding sites and identification of conserved biding motives in Chip-seq experiments
• Analysis of the methylation status of CpG islands

For more information or to discuss state of the art bioinformatics please contact us directly.