By Pharmatrans SANAQ…
IBUPROFEN DC 100 Taste Masking and Direct Compression solution for Ibuprofen Formulations
Problem
Conventional ibuprofen powder is inherently bitter and physically irregular. In oral dispersible formats such as stick packs, sachets, suspensions, and ODTs, this irregular particle nature often leads to poor flow, segregation, and inconsistent coating during taste masking.
Challenges
Formulators then rely on complex taste masking systems, higher sweetener loads, and multiple process adjustments to control bitterness and ensure uniformity. This increases development time, more expensive products, processing variability, and scale up risk, even though the API itself is well known and effective.
Solution
IBUPROFEN DC 100 is the same chemically Ibuprofen molecule presenting, as engineered, near spherical pellets with controlled PSD. IBUPROFEN DC 100 does not remove bitterness but provides physically optimized particles format that easier to coat, blend, and compress for oral dispersible and direct compression formulations.
Proof
The regular pellet structure improves flow, reduces segregation, and enables more consistent coating or encapsulation during taste masking. It also supports robust direct compression, allowing better content uniformity, higher drug loading, and more predictable manufacturing performance.
Takeaway
IBUPROFEN DC 100 simplifies and stabilizes taste masking and direct compression formulations offering a controlled, pelletized API format designed for modern oral dispersible dosage forms enhancing the consumer’s compliance.
Resources
See Pharmatrans SANAQ IBUPROFEN DC 100 for product information.








