Libidosine® food supplement
Products & Services | Laboratoria Smeets S.A
Laboratoria Smeets (LabSmeets) has developed a patented food supplement Libidosine® that combats hormone-related loss of libido, stimulating increased sex drive in men and women.
Loss of libido (decreased sex drive) is a common problem that can affect approximately 20 per cent of men and an even higher proportion of women in developed countries of Northern Europe and North America.Loss of sex drive is often caused by basic psychosexual or emotional factors linked to relationship issues, stress or life events such as pregnancy, childbirth or breastfeeding. Decreased libido can also be linked to alcohol or drug consumption (e.g. anti-depressants), to exhaustion and effects of ageing. However, the most immediate physiological symptoms of erectile dysfunction or vaginal dryness are linked to hormonal imbalances. In older women, levels of the female hormone oestrogen begin to fall as they approach menopause. An underactive thyroid can also cause low libido due to thyroxine hormone deficiency, while raised levels of prolactin in the blood can cause the hormonal condition hyperprolactinaemia that can also reduce sex drive.
Key hormonal factors
However, the key hormones linked to sexual desire and libido are testosterone and dopamine. Older men can develop low testosterone levels, exhibiting as fatigue, depression, and a reduced sex drive. In Testosterone deficiency can also affect libido in women, especially post-hysterectomy. Testosterone is the ‘male hormone’ that fuels masculine behavior traits that paradoxically is also linked to sexual desire in women. Low dopamine levels are also significant in loss of libido since sexual desire involves the brain’s chemical messaging system that relies on dopamine. Doctors have noted that Parkinson’s patients treated with dopamine-stimulating drugs had increased sexual desire, as well as men with hypoactive sexual desire disorder (HSDD). It should be noted that the sexual performance ‘silver bullet’ drugs such as Viagra®, Cialis®, and Levitra® have no effect on desire, only on physical performance post arousal.
Recent research has confirmed testosterone and dopamine levels links with dietary and nutritional factors, such as whole fruit, fibrous vegetables, adequate lean protein, complex carbohydrates, and moderate amounts of healthy monounsaturated fats like avocados, nuts and olives, plus essential fatty acids from fish oils. Conversely, soy-based proteins and protein isolates have been shown to decrease testosterone levels, possibly due to phytoestrogen compounds or impact on the endocrine system. The phytochemical diindolymethane (DIM), found in broccoli, cabbage varieties and cauliflower is also valuable in reducing estrogen production that acts a ‘testosterone blocker’.
Vasodilation (widening of blood vessels) directly affects erectile function by changing the relationship between mean arterial pressure and cardiac output, working to decrease total peripheral resistance (TPR) and blood pressure through relaxation of smooth muscle cells in the tunica media layer of large arteries and smaller arterioles. Vasodilation and its opposite, vasoconstriction, is naturally modulated by local paracrine agents from endothelial cells, especially nitric oxide (NO).
Laboratoria Smeets has developed Libidosine as a nutritional supplement product that is designed to improve sexual desire for men, as well as women. The product works by influencing testosterone and dopamine levels in the body.
Its efficacy is based on extensive research of the biochemical pathways of mechanisms that can restore natural levels of both testosterone and dopamine, with consequent impacts on sexual desire and arousal responses. In addition, Libidosine’s formulation incorporates a major precursor of NO, to increase vasodilatation, enhancing erectile function.