Genetic Toxicology

BSL BIOSERVICE has been performing biological safety and activity testing for more than 25 years. Its highly skilled team is dedicated to providing efficient and accurate results.

BSL BIOSERVICE’s Department of Genetic Toxicology is made up of 30 individuals, 8 scientists (PhD or master in natural sciences) and 14 technicians with 3 years apprenticeship. The team carry out more than 450 studies per year and has knowledge in testing pharmaceuticals, chemicals, agrochemicals as well as medical devices. Results are reliable and conveyed within the shortest timescale possible. BSL BIOSERVICE also provides scientific and regulatory requirement advice specific to your project.

Customised Test Designs
BSL BIOSERVICEoffers efficient assays which require only small amounts of testing material and provide results very fast. Miniaturised and screening tests of the standard testing battery are available for the following assays:
• Bacterial reverse mutation test (AMES)
• Mouse lymphoma assay
• In vitro micronucleus test

BSL BIOSERVICE can also provide exceptional short turnaround standard tests. To ensure test results are accepted worldwide, BSL BIOSERVICE ensures all tests comply with current international guidelines (e.g.ICH, US-FDA, ISO, EMEA, OECD) and are performed in accordance with GLP (Good Laboratory Practice).

BSL BIOSERVICE routine tests include:

In vitro Tests
• Bacterial reverse mutation test (AMES)
• Mouse lymphoma assay
• HPRT assay
• Chromosome aberration test
• Micronucleus test
• Comet assay
• Unscheduled DNA synthesis

In vivo Tests
• Chromosome aberration test
• Micronucleus test
• Comet assay
• Unscheduled DNA synthesis

Additional Testing
• Embryonic stem cell test (EST)
• Syrian hamster embryo (SHE) cell transformation assay

For more information or to discuss genetic toxicology please contact us directly.