Calcium-derived compounds

Introduction

Magnesia has more than three decades experience in calcium compounds, which have played a core role in the company’s history and development.

Calcium (Ca, No. 20) is a mineral that is essential to health and nutrition. The human body contains more calcium (largely in bones and teeth) than any other mineral. Calcium plays a key part in the functions of the muscular, circulation, nervous and blood-clotting systems. The mineral contributes to the normal function of digestive enzymes and plays a key role in the process of cell division and specialization.

Calcium compounds are indicated in treatment of bone conditions including osteoporosis, rickets and osteomalacia. Calcium is also used for muscular cramps, pre-eclampsia, and reducing the risk of colon and rectal cancers.

In diet, calcium compounds are used as an antacid and to reduce phosphate levels in people with kidney disease.

The organic compounds, such as calcium carbonate, citrate, chelatecalcium citrate, lactate, gluconate and aspartate, exhibit wide bioavailability making them particularly useful in medicines and nutrition.

Magnesia offers a wide range of organic and inorganic compounds derived from calcium to the pharmaceutical, food and cosmetics industries. These compounds are supplied in MagGran® granular form and in the Magnesia powder and other forms detailed below.

Benefits

All Magnesia-supplied calcium compounds are selected for purity, nutraceutical quality and optimum bioavailability.

Magnesia maintains very high service levels with samples available immediately and orders commissioned and packaged according to customer requirements, with Just In Time (JIT) delivery.

For each product, full documentation is available that detail each step from production to final delivery, to correspond with international pharmacopoeias and regulatory requirements (see Quality & Certification section below).

Product portfolio

All Magnesia calcium compounds products are specified to European Pharmacopoeia (Ph.Eur.), US Pharmacopoeia Convention (USP), German Pharmacopoeia (DAB), Food Chemicals Codex (FCC) and International food E-number standards. Compounds are grouped by process.

Carbonates

Product	Compound	Grade	Standard(s)
Magnesia 442	Calcium carbonate	Light 320 g/l	Ph. Eur., E 170
Magnesia 452	Calcium carbonate	Light 480 g/l	Ph. Eur., USP, E 170
Magnesia 446	Calcium carbonate	Medium heavy 700 g/l (tapped)	Ph. Eur., BP, USP, JP, E 170
Magnesia 449/4491	Calcium carbonate	Heavy 760 g/l	Ph. Eur., USP, E 170, FCC
Magnesia 444	Calcium carbonate	Heavy 900 – 1.100 g/l	Ph. Eur., low iron
Magnesia 464	Calcium carbonate	Heavy 1,100 g/l	Ph. Eur., USP, E 170, D50: 40-45 μm

 

Hydroxide

Magnesia 7245

Calcium hydroxide

Powder 400 g/l

Ph. Eur., USP, FCC, E 526

 

Oxide

Magnesia 7258

Calcium oxide

Powder 800 g/l

FCC, E 529

 

Chlorides

Magnesia 4155	Calcium chloride	2-hydrate, crystalline	Ph. Eur., USP, E 509
Magnesia 4156	Calcium chloride	6-hydrate, crystalline	E 509

 

Citrates

Magnesia 7456	Mono-Calcium citrate	1-hydrate	E 333
Magnesia 7231	Tri-Calcium citrate	4-hydrate	DAC or USP, FCC or E 333
Magnesia 7421	Tri-Calcium citrate	Anhydrous	USP or E 333

 

Stearates

Magnesia 4273	Calcium stearate	Ca: 6.4 – 7.1 %, vegetable	Ph. Eur., BP, USP / NF, FCC, JP
Magnesia 4274	Calcium stearate	Ca: 6.4 – 7.4 %, vegetable	Ph. Eur., USP/NF, E 470a

 

Sulphate

Magnesia 7271

Calcium sulphate

2-hydrate

Pharmaceutical / food grade

 

Further compounds

Magnesia 7219	Calcium acetate	Containing water	Ph. Eur. or USP or E 263
Magnesia 7222	Calcium ascorbate	2-hydrate	Ph. Eur., USP
Magnesia 7240	Calcium gluconate	1-hydrate	Ph. Eur. or USP
Magnesia 7249	Calcium lactate	5-hydrate	FCC or USP

 

Quality & Certification

Product standards and documentation is defined by international pharmacopoeias, by the Food Chemicals Codex (FCC) or the food law of the European Union. Upon request Magnesia can also provide data formatted for European Certificates of Suitability (CEP) or US Drug Master Files (DMF) providing all relevant information about the substance. Magnesia can also provide data to support health claims made under European Food Safety Agency (EFSA) requirements.

All Magnesia processes are certified to ISO 90001 standards and follow HACCP hygiene management protocols.

Resources

Click on Magnesia’s calcium compounds for more information.
Click on Magnesia to contact the company directly.

---

Supplier Information
Supplier: Magnesia GmbH
Address: Max-Jenne-Str. 2-4 in 21337 Lüneburg, Germany
Tel: +49 4131 8710 0
Fax: +49 4131 8710 55
Website: www.magnesia.de/

---